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KMID : 0043319970200030201
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Archives of Pharmacal Research
1997 Volume.20 No. 3 p.201 ~ p.205
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Anticomplementary Activity of Ergosterol Peroxide from Naematoloma fasciculare and Reassignment of NMR Data
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Kim Dong-Seon
Baek Nam-In
Oh Sei-Ryang
Jung Keun-Young
Lee Im-Seon
Kim Jung-Hee
Lee Hyeong-Kyu
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Abstract
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A very high content (at least 0.23%) of ergosterol peroxide was isolated from Naematoloma fasciculare Karst. Not only ergosterol peroxide but also ergosterol showed very strong anticomplementary activity on the classical pathway, the values being and , respectively. The and NMR data of ergosterol peroxide were revised and completely assigned by DEPT, COSY, HMQC and HMBC correlations.
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KEYWORD
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Naematoloma fasciculare, Anticomplementary activity, Ergosterol, Ergosterol peroxide, NMR. HMBC
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